Location of the multimerin 1 binding site in coagulation factor V: An update
نویسندگان
چکیده
منابع مشابه
The Functions of the A1A2A3 Domains in Von Willebrand Factor Include Multimerin 1 Binding
Multimerin 1 (MMRN1) is a massive, homopolymeric protein that is stored in platelets and endothelial cells for activation-induced release. In vitro, MMRN1 binds to the outer surfaces of activated platelets and endothelial cells, the extracellular matrix (including collagen) and von Willebrand factor (VWF) to support platelet adhesive functions. VWF associates with MMRN1 at high shear, not stati...
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ژورنال
عنوان ژورنال: Thrombosis Research
سال: 2008
ISSN: 0049-3848
DOI: 10.1016/j.thromres.2008.03.016